28 phlove
Still no deal: Albany teachers strike enters third week
NoneMILAN, Italy (Reuters) -Inter Milan toiled to a 2-0 victory over lowly Como thanks to second-half goals from Carlos Augusto and Marcus Thuram on Monday to remain within touching distance of the Serie A summit. The win lifted third-placed Inter to 37 points, leaving them three points off leaders Atalanta, who beat Empoli 3-2 on Sunday, and one behind second-placed Napoli, after they won 2-1 at Genoa on Saturday. Inter have a game in hand on the top two. Defending champions Inter dominated the first half but squandered a number of chances, with the unmarked Denzel Dumfries firing over from close range and Federico Dimarco shooting straight at Como’s veteran goalkeeper Pepe Reina. Inter finally scored with Augusto’s towering far-post header from a Hakan Calhanoglu corner three minutes after the break. “Happy for the goal, but more important is the victory. We knew it was a tough game but we got three points,” left back Augusto told Sky Italia. “We knew it was a different league last year, this year there are many strong teams. But I have confidence in my team mates who are the best in the world. We’ll see at the end”. The visitors looked more dangerous after going behind, with man of the match Augusto making a crucial interception to deny Edoardo Goldaniga an equaliser and Yann Sommer pulling off a great save to keep out an effort from Nico Paz. Inter kept pushing to extend their lead but captain Lautaro Martinez saw his 68th-minute effort disallowed for offside, extending his goal drought that has lasted more than a month. Thuram sealed the win two minutes into stoppage time with a powerful shot past Reina to reach 12 league goals, level with Atalanta’s Mateo Retegui in the Serie A scoring chart. “Even in matches in which we are not 100% brilliant, it’s important to win,” said Inter centre-back Alessandro Bastoni. “Especially because the others had already played and won, so we had to give a positive response.” (Reporting by Janina Nuno Rios in Mexico City; Editing by Ken Ferris) Disclaimer: This report is auto generated from the Reuters news service. ThePrint holds no responsibility for its content. var ytflag = 0;var myListener = function() {document.removeEventListener('mousemove', myListener, false);lazyloadmyframes();};document.addEventListener('mousemove', myListener, false);window.addEventListener('scroll', function() {if (ytflag == 0) {lazyloadmyframes();ytflag = 1;}});function lazyloadmyframes() {var ytv = document.getElementsByClassName("klazyiframe");for (var i = 0; i < ytv.length; i++) {ytv[i].src = ytv[i].getAttribute('data-src');}} Save my name, email, and website in this browser for the next time I comment. Δ document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() );
CHANHASSEN, Minn. , Nov. 24, 2024 /PRNewswire/ -- Alpheus Medical, Inc., a private, clinical-stage oncology company pioneering sonodynamic therapy (SDT) for the treatment of solid body cancers, today announced positive results from their Phase 1/2 clinical trial in patients with recurrent or refractory high-grade gliomas. The company's proprietary therapy demonstrated a strong safety profile and extended median overall survival (OS) and progression-free survival (PFS) compared to historical data. The data were presented by Michael Schulder , MD, at the 2024 Society of Neuro-Oncology (SNO) Annual Meeting. "Glioblastomas are the most common and aggressive primary brain cancer, presenting a devasting diagnosis for patients and their familes," said David Reardon , MD, Clinical Director of the Center for Neuro-Oncology at Dana-Farber Cancer Institute, and member of the Alpheus Medical Scientific Advisory Board. "Current treatment options are limited and often ineffective due to the diffuse spread of the disease across the blood-brain barrier and often across the entire hemisphere, making it universally fatal with a rapid timeline. The early clinical results of Alpheus's therapy are promising, offering hope for this new approach. I look forward to further exploring the potential benefits of their SDT therapy for this patient population who is in critical need of an effective solution." Alpheus Medical's non-invasive SDT treatment, which can be delivered in an outpatient setting, combines low-intensity diffuse ultrasound (LIDU TM ) with oral 5-aminolevulinic acid (5-ALA) to target and kill cancer cells across the entire hemisphere without the need for imaging or sedation. Key findings from the study include: "In addition to the strong safety data and early indications of efficacy, Alpheus' non-invasive SDT therapy stands out for its ease of use - a significant improvement over the uncomfortable and often toxic treatments currently available for this rapidly fatal condition," stated Dr. Schulder, Director of the Brain Tumor Center at Northwell Health, and one of the trial's primary investigators. "We look forward to expanding the ability for patients to receive this promising therapy." The Phase 1/2 trial ( NCT05362409 ) is an open-label, multicenter, duration-escalation study evaluating the safety, optimal dose, and efficacy of Alpheus Medical's proprietary SDT platform. Twelve patients were enrolled across three cohorts, with treatment durations escalating to 60, 90, and 120 minutes per monthly session. The company plans to initiate a randomized, controlled trial at multiple centers across the U.S. in 2025. About Alpheus Medical, Inc. Alpheus Medical is a private, clinical-stage oncology company revolutionizing the treatment of solid body cancers with its pioneering sonodynamic therapy (SDT) platform that combines Low-Intensity Diffuse Ultrasound (LIDU TM ) with the sensitizing agent, oral 5-aminolevulinic acid (5-ALA). The company's proprietary, non-invasive technology is designed to selectively target and destroy cancer cells in the brain while preserving healthy tissue. Learn more at www.alpheusmedical.com . Media Contact Carla Benigni [email protected] View original content to download multimedia: https://www.prnewswire.com/news-releases/alpheus-medical-announces-positive-phase-12-trial-results-for-the-treatment-of-recurrent-high-grade-gliomas-302314785.html SOURCE Alpheus MedicalFantasy Football is all about the matchups. Even though you drafted your team with certain hopes and intentions, your weekly lineup decisions shouldn't be determined by the order you picked your players in. You need to check who your players play and make sure you've got the right guys in -- and the wrong guys out. It's too early to be absolutely sure which matchups will be easy and which ones will be tough, but we can take some educated guesses based on healthy personnel, defensive schemes, track records, and key details of offenses. The things we know can help us minimize the impact of the things we don't know. This should lead to better decisions being made. We'll go through every game and highlight the players who aren't obvious starts and sits (because you don't need to be told to start Derrick Henry ). You should feel more comfortable starting or sitting players based on the information given, and feeling comfortable with your Fantasy lineup before the games start is the best feeling in the world. More Week 17 content: Heath Cummings' Full Week 17 Projections OBVIOUS STARTS: Travis Kelce STARTS: Patrick Mahomes (low-end starter), George Pickens (No. 2 WR), Chiefs DST FLEX: Xavier Worthy , Jaylen Warren (PPR), Najee Harris SITS: Russell Wilson , Marquise Brown , DeAndre Hopkins , Pat Freiermuth , Isiah Pacheco , Kareem Hunt , Samaje Perine , Calvin Austin, Steelers DST OBVIOUS STARTS: Lamar Jackson , Derrick Henry , Nico Collins STARTS: Joe Mixon (No. 2 RB), Mark Andrews , Ravens DST, Dalton Schultz (low-end starter) FLEX: Zay Flowers , Rashod Bateman SITS: C.J. Stroud , John Metchie, Isaiah Likely , Robert Woods , Dare Ogunbowale , newest Texan Diontae Johnson , Texans DST STARTS: Caleb Williams , Geno Smith (borderline starter), Zach Charbonnet (as long as Ken Walker is out), Jaxon Smith-Njigba (top-15 WR), Keenan Allen , D.J. Moore (No. 2 PPR WR), D'Andre Swift , Seahawks DST FLEX: DK Metcalf SITS: Rome Odunze , Tyler Lockett , Cole Kmet , A.J. Barner, Bears DST STARTS: Justin Herbert (low-end starter), Ladd McConkey (No. 2 WR), Hunter Henry (low-end TE), Chargers DST (low-end starter) FLEX: Rhamondre Stevenson SITS: Drake Maye , Gus Edwards (desperation RB), Quentin Johnston (desperation WR), Stone Smartt , Kayshon Boutte , Austin Hooper , Demario Douglas , Kendrick Bourne , Antonio Gibson , Kimani Vidal , Patriots DST OBVIOUS STARTS: Joe Burrow , Chase Brown , Ja'Marr Chase , Tee Higgins STARTS: Bo Nix , Courtland Sutton (No. 1 WR) SITS: Javonte Williams (desperation RB), Audric Estime , Adam Trautman , Andrei Iosivas , Devaughn Vele , Mike Gesicki , Bengals DST (borderline DST), Broncos DST OBVIOUS STARTS: Kyren Williams , Puka Nacua , Cooper Kupp (No. 2 WR), Trey McBride STARTS: Rams DST SITS: Kyler Murray , Matthew Stafford , Marvin Harrison Jr. , Michael Carter , Demarcus Robinson , Michael Wilson , Tyler Higbee , Cardinals DST OBVIOUS STARTS: Josh Allen , Davante Adams STARTS: James Cook , Breece Hall (No. 2 RB), Garrett Wilson , Bills DST FLEX: Khalil Shakir SITS: Aaron Rodgers , Dalton Kincaid (borderline No. 1/No. 2 TE), Tyler Conklin , Allen Lazard , Ty Johnson (desperation PPR RB), Keon Coleman , Amari Cooper , Braelon Allen , Mack Hollins , Jets DST STARTS: Brian Thomas Jr. , Tony Pollard , Chig Okonkwo FLEX: Calvin Ridley , Travis Etienne , Tyjae Spears (PPR) SITS: Mason Rudolph , Mac Jones , Tank Bigsby , Nick Westbrook-Ikhine , Parker Washington , Brenton Strange , Titans DST, Jaguars DST OBVIOUS STARTS: Justin Jefferson , Josh Jacobs , Jordan Addison STARTS: Sam Darnold , Aaron Jones , Tucker Kraft FLEX: Romeo Doubs (PPR) SITS: Jordan Love , Jayden Reed (low-end flex), Dontayvion Wicks , T.J. Hockenson , Cam Akers , Vikings DST (low-end starter), Packers DST OBVIOUS STARTS: Brock Bowers STARTS: Jakobi Meyers (low-end No. 2 WR), Alexander Mattison (low-end No. 2 RB), Ameer Abdullah (low-end No. 2 PPR RB) SITS: Aidan O'Connell , Spencer Rattler , Kendre Miller , Foster Moreau , Juwan Johnson , Raiders DST (desperation DST), Saints DST OBVIOUS STARTS: Malik Nabers (No. 2 WR) STARTS: Tyrone Tracy Jr . (No. 2 RB) SITS: Drew Lock , Darius Slayton , Wan'Dale Robinson , Devin Singletary , Dan Bellinger, Giants DST OBVIOUS STARTS: Mike Evans , Chuba Hubbard STARTS: Baker Mayfield , Bucky Irving FLEX: Adam Thielen (borderline No. 2 PPR WR), Jalen McMillan , Rachaad White SITS: Bryce Young , Jalen Coker , Payne Durham , Ja'Tavion Sanders , Buccaneers DST, Panthers DST OBVIOUS STARTS: De'Von Achane , Tyreek Hill (No. 2 WR) STARTS: Jerome Ford (No. 2 RB), Jonnu Smith , David Njoku , Dolphins DST SITS: Tua Tagovailoa (borderline starter), Dorian Thompson-Robinson , Jerry Jeudy , Malik Washington , Elijah Moore , Raheem Mostert , D'Onta Foreman , Browns DST OBVIOUS STARTS: Saquon Barkley , CeeDee Lamb , A.J. Brown STARTS: Rico Dowdle (low-end No. 2 RB), Eagles DST FLEX: DeVonta Smith SITS: Kenny Pickett , Cooper Rush , Jake Ferguson (low-end PPR TE), Brandin Cooks , Ezekiel Elliott , Cowboys DST OBVIOUS STARTS: Bijan Robinson STARTS: Jayden Daniels , Terry McLaurin , Drake London , Brian Robinson Jr. , Commanders DST FLEX: Darnell Mooney SITS: Michael Penix Jr. , Olamide Zaccheaus , Zach Ertz , Kyle Pitts , Ray-Ray McCloud , Tyler Allgeier , Jeremy McNichols , Falcons DST OBVIOUS STARTS: Jahmyr Gibbs , Amon-Ra St. Brown , George Kittle STARTS: Jared Goff , Sam LaPorta , Lions DST FLEX: Deebo Samuel , Jauan Jennings SITS: Brock Purdy , Patrick Taylor , Tim Patrick , Craig Reynolds , 49ers DSTIs the world more dangerous than ever for travelers? A global risk expert weighs in