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2025-01-12

NEW YORK , Dec. 10, 2024 /PRNewswire/ -- Report on how AI is redefining market landscape - The global iron castings market size is estimated to grow by USD 50.34 billion from 2024 to 2028, according to Technavio. The market is estimated to grow at a CAGR of 5.98% during the forecast period. For comprehensive forecast and historic data on regions,market segments, customer landscape, and companies- Click for the snapshot of this report Region Outlook 1. APAC - APAC is estimated to contribute 68%. To the growth of the global market. The Iron Castings Market report forecasts market growth by revenue at global, regional & country levels from 2017 to 2027. The iron castings market in the APAC region is projected to expand during the forecast period due to the region's rapid industrialization and substantial infrastructure development. The demand for iron castings is linked to the construction of new infrastructure projects such as roads, bridges, buildings, and industrial facilities. The growth of manufacturing industries and sectors like heavy machinery, industrial equipment, and machine tools in APAC drive the demand for iron castings. These castings are vital components in industrial machinery. Furthermore, the burgeoning construction sector in APAC, fueled by urbanization and population growth, increases the demand for iron castings in construction equipment, structural components, and automotive components. For more insights on APAC's significant contribution along with the market share of rest of the regions and countries - Download a FREE Sample Segmentation Overview 1.1 Automobile 1.2 Industrial machinery 1.3 Infrastructure and construction machines 1.4 Power 1.5 Pipe fittings and others 2.1 Gray iron 2.2 Duct iron 2.3 Malleable iron 3.1 APAC 3.2 Europe 3.3 North America 3.4 South America 3.5 Middle East and Africa Get a glance at the market contribution of rest of the segments - Download a FREE Sample Report in minutes! 1.1 Fastest growing segment: The automotive industry's reliance on iron castings for manufacturing durable and critical components, such as engine blocks, cylinder heads, brake discs, drums, and transmission housings, is significant. These components' excellent heat dissipation, high strength, and ability to withstand high temperatures and pressures make iron castings an ideal material choice. Gray and ductile iron are commonly used for different applications due to their distinct properties. The global production of vehicles, particularly in leading manufacturing hubs like Germany , South Korea , Japan , India , China , and the US, is on the rise. In 2021, these countries produced a combined total of approximately 43,131 million cars. This increasing volume of vehicle production will subsequently fuel the demand for iron castings, driving the growth of the global iron castings market during the forecast period. Research Analysis The global iron castings market is a significant segment of the foundry industry, supplying metal components for various industries such as automotive and machinery production. The market's growth is driven by the demand for durable and high-performance metal components. The foundry operations involved in the production of iron castings require precise control of metallurgical properties, heat treatment, machining processes, and surface finishing to meet customer preferences and ensure product differentiation. The global market for iron castings is influenced by several trends, including cost optimization, innovation, and regulatory compliance. Foundry capacity expansion, market segmentation, and regional markets are key areas of focus for industry players. Trade policies, market challenges, and industry partnerships also impact the market dynamics. Energy efficiency, waste management, workforce training, and digitalization trends are essential considerations for foundries to remain competitive. Predictive maintenance, customer engagement, and brand positioning are critical for customer satisfaction and aftermarket services. Material sourcing and regulatory compliance are also crucial aspects of the industry. The iron castings market is expected to grow significantly in the coming years, driven by the automotive sector and machinery production. Market research and forecasts indicate a positive outlook for the industry, with a focus on product innovation, cost optimization, and customer preferences. The steel industry's trends, such as innovation and digitalization, also influence the iron castings market. Market Overview The global Iron Castings market is a significant segment of the foundry industry, supplying metal components for various industries. The market caters to the automotive sector for engine blocks, cylinder heads, and other critical parts, as well as machinery production for gears, pumps, and other machinery components. The global market is driven by the steel industry's demand for raw materials, casting processes like investment casting, sand casting, and ductile iron and gray iron production. Quality standards, supply chain, and foundry equipment are essential factors in the industry. Emerging economies and technological advancements are shaping the market, with demand trends in end-user industries like automotive and machinery production. Pricing strategies, environmental regulations, and sustainable practices are also crucial considerations. Foundry operations face challenges like casting defects, metallurgical properties, heat treatment, and machining processes. Surface finishing, product differentiation, and customer preferences drive innovation trends. Cost optimization, foundry capacity, and market segmentation are essential for market growth. Regional markets, trade policies, and regulatory compliance are significant market challenges. Industry associations, market research, and market forecasts provide valuable insights. Customer satisfaction, aftermarket services, material sourcing, energy efficiency, waste management, workforce training, and digitalization trends are shaping the future of the Iron Castings market. Start exploring market insights by Download a FREE Sample Report in minutes! Key Topics Covered: 1 Executive Summary 2 Market Landscape 3 Market Sizing 4 Historic Market Size 5 Five Forces Analysis 6 Market Segmentation 7 Customer Landscape 8 Geographic Landscape 9 Drivers, Challenges, and Trends 10 Venodr Landscape 11 Vendor Analysis 12 Appendix About Technavio Technavio is a leading global technology research and advisory company. Their research and analysis focuses on emerging market trends and provides actionable insights to help businesses identify market opportunities and develop effective strategies to optimize their market positions. With over 500 specialized analysts, Technavio's report library consists of more than 17,000 reports and counting, covering 800 technologies, spanning across 50 countries. Their client base consists of enterprises of all sizes, including more than 100 Fortune 500 companies. This growing client base relies on Technavio's comprehensive coverage, extensive research, and actionable market insights to identify opportunities in existing and potential markets and assess their competitive positions within changing market scenarios. Contacts Technavio Research Jesse Maida Media & Marketing Executive US: +1 844 364 1100 UK: +44 203 893 3200 Email: [email protected] Website: www.technavio.com/ SOURCE Technaviojili178 review

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Nearly half of low-income families do not use social fund support for their children. This is evident from research that ABN Amro conducted together with the Youth Fund for Sport & Culture. Approximately 1.2 million people have to survive on an income around the poverty line. They may, therefore, be eligible for support for additional expenses for their children, for things like sports and cultural activities. However, almost half of the families do not use this. People with work and a low income are especially reluctant to ask for support. Uncertainty about the application criteria and shame in asking for help play an important role, according to the researchers. Many parents also fear complicated procedures and think that the money may have to be repaid. People on benefits or social assistance often ask for support. Funds that parents can call on include the Leergeld Foundation, the Youth Sports & Culture Fund, and the Jarige Job Foundation. According to the researchers, it is noticeable that once people use a fund, the threshold for applying to other social funds becomes lower. For example, 15 percent of families have applied for a facility from two and 19 percent from three or more funds.A frog holding a taro-leaf umbrella. A parade of frolicking animals. An Ukiyo-e style Mount Fuji. Giant waves. A Japanese artist who goes by the name Lito carves these delicate designs on fallen leaves, giving life back to them. The world of Lito’s delicate art, which he began in 2020 and posts on social media almost daily, has won fans around the world. The leaf art also provided him solace after earlier struggles with attention-deficit hyperactivity disorder, and a purpose in life — the joy of making people happy with his art. He enjoys working at night. From a pile of leaves treated with a wrinkle-free chemical, he picks one and places it on a cutting board. First, he outlines the design on the leaf with a pen in his right hand. Then he takes a design knife in his left hand and starts cutting the leaf carefully. Slowly, the leaf begins to take the shape of a frog carrying an umbrella — a simple design he demonstrated in a recent interview. More complex, highly intensive work on a single leaf can take more than eight hours to complete. His leaf-cutting works include titles such as “Scrolls of Frolicking Animals,” “Leaf Aquarium,” and “Thirty-six Views of Mt. Fuji: The Great Wave off Kanagawa.” Each piece includes his own twists and often uses animals. “I would rather finish it in one go when I am focused,” said Lito, 38. He didn’t want to disclose his real name for personal reasons. Since his childhood, Lito said he has had high levels of concentration and patience. But he had trouble fitting into what was considered the norm at school or at work, despite all his efforts. He struggled to interpret others’ feelings and to avoid confrontations. After years of difficulty, he went to a hospital at age 30 and was told he has ADHD, a diagnosis he felt explained why he always did things differently. He saw no point in forcing himself to do things the same way as other people and began to adjust his life. In early 2020, Lito came across the art of leaf cutting. He saw it as the perfect use of his patience and concentration. Word of his skills spread across social media, and he published books on his leaf-cutting work. He holds a near-monthly solo exhibition in various places in Japan. “If I can make people happy by doing what I am doing, I want to do more. That’s my driving force for what’s next,” Lito said. Be the first to know Get local news delivered to your inbox!

NEW YORK — Eager to preserve President-elect Donald Trump's hush money conviction even as he returns to office, prosecutors suggested various ways forward — including one based on how some courts handle criminal cases when defendants die. In court papers made public Tuesday, the Manhattan district attorney's office proposed an array of options for keeping the historic conviction on the books. The proposals include freezing the case until Trump is out of office, or agreeing that any future sentence wouldn't include jail time. Another idea: closing the case with a notation that acknowledges his conviction but says that he was never sentenced and his appeal wasn't resolved because of presidential immunity. Former President Donald Trump appears in Manhattan criminal court May 30 during jury deliberations in his criminal hush money trial in New York. The last is adopted from what some states do when a criminal defendant dies after being convicted but before appeals are exhausted. It is unclear whether that option is viable under New York law, but prosecutors suggested that Judge Juan M. Merchan could innovate in what's already a unique case. "This remedy would prevent defendant from being burdened during his presidency by an ongoing criminal proceeding," prosecutors wrote. But at the same time, it wouldn't "precipitously discard" the "meaningful fact that defendant was indicted and found guilty by a jury of his peers." Expanding on a position they laid out last month, prosecutors acknowledged that "presidential immunity requires accommodation during a president's time in office," but they were adamant that the conviction should stand. They argued that Trump's impending return to the White House should not upend a jury's finding. Trump wants the case to be thrown out in light of his election. His communications director, Steven Cheung, called prosecutors' filing "a pathetic attempt to salvage the remains of an unconstitutional and politically motivated hoax." Trump has fought for months to reverse his conviction on 34 counts of falsifying business records. Prosecutors said he fudged the documents to conceal a $130,000 payment to porn actor Stormy Daniels to suppress her claim that they had sex a decade earlier. Former President Donald Trump returns to the courtroom May 30 at Manhattan Criminal Court in New York. He says they did not and denies wrongdoing. Trump portrays the case as a political attack ginned up by District Attorney Alvin Bragg and other Democrats. Trump's legal team argues that letting the case continue would present unconstitutional "disruptions" to his upcoming presidential term. Trump's attorneys also cited President Joe Biden's recent pardon of his son Hunter Biden, who was convicted of tax and gun charges. Biden complained that his son was unfairly prosecuted for political reasons — and Trump's lawyers say he was, too. Trump's lawyers argued that the possibility of a jail sentence — even if it's after he leaves office — would affect his presidency. Prosecutors suggested Merchan could address that concern by agreeing not to put him behind bars. It's unclear how soon Merchan could decide what to do next with the case. He could grant Trump's request for dismissal, go with one of the suggestions from prosecutors, wait until a federal appeals court rules on Trump's parallel effort to get the case moved out of state court, or choose some other option. Trump, a Republican, takes office Jan. 20. Former President Donald Trump gestures May 31 as he leaves a news conference at Trump Tower in New York. He was scheduled for sentencing late last month. After Trump's Nov. 5 election win, Merchan halted proceedings and indefinitely postponed the former and future president's sentencing so the defense and prosecution could weigh in on the future of the case. Merchan also delayed a decision on Trump's prior bid to dismiss the case on immunity grounds. A dismissal would erase Trump's conviction, sparing him the cloud of a criminal record and possible prison sentence. Trump is the first former president to be convicted of a crime and the first convicted criminal to be elected to the office. The hush money case was the only one of Trump's four criminal indictments to go to trial. Since the election, special counsel Jack Smith ended his two federal cases, which pertained to Trump's efforts to overturn his 2020 election loss and allegations that he hoarded classified documents at his Mar-a-Lago estate. A separate state election interference case in Fulton County, Georgia, is largely on hold. Trump denies wrongdoing in each case. Former President Donald Trump speaks outside the courtroom after a jury convicted him of felony crimes for falsifying business records in a scheme to illegally influence the 2016 election, at Manhattan Criminal Court in New York, Thursday, May 30, 2024. (Steven Hirsch/New York Post via AP, Pool) Former President Donald Trump sits in Manhattan criminal court, on May 13, 2024, in New York. (Sarah Yenesel/Pool Photo via AP) Former President Donald Trump talks to the media outside Manhattan criminal court in New York, on May 14, 2024. (Curtis Means/Pool Photo via AP) Former President Donald Trump appears at Manhattan criminal court before his trial in New York, on April 30, 2024. (Justin Lane/Pool Photo via AP) Michael Cohen, right, leaves his apartment building in New York, on May 14, 2024. (AP Photo/Seth Wenig) Former President Donald Trump appears at Manhattan criminal court during jury deliberations in his criminal hush money trial in New York, Thursday, May 30, 2024. (Mark Peterson/Pool Photo via AP) Former President Donald Trump awaits the start of proceedings in Manhattan Criminal Court, on May 28, 2024, in New York. (AP Photo/Julia Nikhinson, Pool) Former President Donald Trump appears at Manhattan criminal court during jury deliberations in his criminal hush money trial in New York, Thursday, May 30, 2024. (Steven Hirsch/New York Post via AP, Pool) From left North Dakota Gov. Doug Burgum, U.S. Speaker of the House Mike Johnson and businessman Vivek Ramaswamy look on as former President Donald Trump talks to the media as he arrives at Manhattan criminal court in New York, on May 14, 2024. (Curtis Means/Pool Photo via AP) A supporter of former President Donald Trump reads a "Jews for Trump" sign outside Manhattan Criminal Court, on May 29, 2024, in New York. (AP Photo/Julia Nikhinson) Donald Trump, Jr. speaks to reporters across the street from former President Donald Trump's criminal trial in New York, on May 28, 2024. (AP Photo/Seth Wenig) A supporter of former President Donald Trump and an anti-Trump protester fight outside Manhattan Criminal Court, Thursday, May 30, 2024, in New York. (AP Photo/Julia Nikhinson) Robert De Niro, center, argues with a Donald Trump supporter after speaking to reporters in support of President Joe Biden across the street from Trump's criminal trial in New York, on May 28, 2024. (AP Photo/Seth Wenig) Donald Trump Jr. speaks outside Manhattan criminal court, on May 21, 2024, in New York. (AP Photo/Julia Nikhinson) Former President Donald Trump talks to the media after a day of testimony in his trial at Manhattan Criminal court in New York, on May 10, 2024. (Jeenah Moon/Pool Photo via AP) Rep. Troy Nehls, R-Texas, wears a tie with photographs of former President Donald Trump during a press conference outside Manhattan criminal court, on May 21, 2024, in New York. (AP Photo/Julia Nikhinson) Trump supporters wave flags and cheer as the motorcade carrying former President Donald Trump leaves the Manhattan Criminal court, on May 13, 2024, in New York. (AP Photo/Stefan Jeremiah) Former President Donald Trump, seen through a camera viewfinder, speaks to members of the media at Manhattan criminal court in New York, on May 2, 2024. (Jeenah Moon/Pool Photo via AP) Former President Donald Trump gestures as he returns to court after a lunch break, at Manhattan criminal court in New York, on May 16, 2024. (Mike Segar/Pool Photo via AP) Former President Donald Trump speaks to reporters at Manhattan Criminal Court on May 21, 2024 in New York. (Michael M. Santiago/Pool Photo via AP) Supporters of former President Donald Trump gather in Collect Pond Park outside Manhattan Criminal Court, Thursday, May 30, 2024, in New York. (AP Photo/Julia Nikhinson) Former President Donald Trump closes his eyes, during his trial at Manhattan criminal court on May 16, 2024, in New York. (Mike Segar/Pool Photo via AP) Former President Donald Trump sits in the courtroom during his criminal trial at the Manhattan criminal court in New York, on May 6, 2024. (Brendan McDermid/Pool Photo via AP) Former President Donald Trump walks to the courtroom at Manhattan criminal court as jurors are expected to begin deliberations in his criminal hush money trial in New York, on May 29, 2024. (Charly Triballeau/Pool Photo via AP) Former President Donald Trump leaves Trump Tower on his way to Manhattan criminal court, on April 15, 2024, in New York. (AP Photo/Yuki Iwamura) Former President Donald Trump sits in Manhattan Criminal Court in New York, on May 20, 2024. (Dave Sanders/The New York Times via AP, Pool) Get the latest in local public safety news with this weekly email.

Ellen DeGeneres & Portia de Rossi Celebrate in U.K. After Leaving U.S.

Australia news LIVE: Bills on the brink in final sitting week of the year; Social media giants slam ‘rushed’ ban consultationORCHARD PARK, N.Y. — In losing Sunday’s battle with the Buffalo Bills, perhaps the best team in football, Jerod Mayo won the war. Best I can tell, he’s staying put. For 2025, and maybe beyond. To his angry fan base and incredulous pockets of the New England Patriots’ media corps, remember Mayo’s future doesn’t hinge on winning this season. It’s not about what you want, or what I think. It’s about the Krafts, who hand-picked Mayo to succeed Bill Belichick four and a half years before he actually did, believing in him, and finding reasons to maintain that belief. In the eyes of someone who wants to believe, Sunday supplied enough reason. The Patriots led at halftime, then lost by three as 14-point underdogs. They became the first team since mid-October to hold the Bills under 30 points. Drake Maye outplayed the next MVP of the league for most of the game and took another step toward his destiny as a franchise quarterback, If that sounds like a low bar, that’s because it is. Such is life in Year 1 of a rebuild, a multi-year process ownership has committed to seeing through to the end with their organizational pillars now in place: Mayo, Maye and de facto GM Eliot Wolf. As frustrating as this 3-12 campaign has been, there are always nuggets of optimism amid the rubble of a losing season; particularly if you want to find them. The Krafts do, and so does Maye, who loves his head coach, by the way; calling questions about Mayo’s job security “BS.” “We’ve got his back,” Maye said post-game. Maye’s voice matters. Certainly more than any number of fans or media members. Ever since media-fueled speculation that Mayo could get canned at the end of his first season began rising, the caveat has always been the same: if, a Gillette Stadium-sized “if,” the Patriots bomb atomically down the stretch, ownership could pull the plug on Mayo. NFL Network insider Ian Rapoport became the latest to join that chorus Sunday with this pregame report: “The Krafts want to keep Jerod Mayo,” he said. “They believe he is the leader for the organization for the future, and they knew it would be a multi-year process to get this thing right. Now if things go off the rails, if they really start to struggle and he loses the locker room the last couple games of the season, we’ve seen this thing turn. “But as of now, the Patriots believe Jerod Mayo is their leader for the future.” Well, Mayo hasn’t lost the locker room. That’s a fact. To a man, both in public and from those I’ve spoken to in private, Patriots players believe in their head coach. Mayo might be a players’ coach, yes, in the best and worst senses. But the Patriots were a few plays away Sunday from pulling off their largest upset since Super Bowl XXXVI. “I think we’re building something good,” Maye said. The Patriots also played their best half of football this season against their toughest opponent yet. Another fact. Now, to the frustrated, I am with you. To the shocked, I understand. But to the trigger-happy, lay down your arms. Mayo, by all accounts, is returning in 2025. Alex Van Pelt, however, is another story. In the same vein that the Krafts could have viewed Sunday’s performance as a reason to save Mayo — despite his pathetic punt at midfield, down 10 with just eight and a half minutes left — they could have convinced themselves their offensive coordinator is the real problem. After all, team president Jonathan Kraft was visibly exasperated over Van Pelt’s play-calling during the Pats’ loss at Arizona a week earlier. Four days later, Van Pelt told reporters he had yet to hear from his boss. Well, that time may be coming. Trailing by three in the fourth quarter Sunday, Van Pelt called a pass that resulted in an unnecessary lateral and game-winning touchdown for Buffalo. His offense later operated like it was taking a Sunday drive with the game on the line, using up 3:16 of the final 4:19 en route to its final touchdown. Van Pelt, finally, weaponized Maye’s legs in critical situations, something that arguably should have been done weeks ago. Not to mention, Van Pelt’s top running back can’t stop fumbling, and the offensive line remains a hot mess. Call him Alex Van Fall Guy. Because Van Pelt’s offense, for the first time in a while, under-performed relative to Mayo’s defense. On merit, he deserves to stay; a case that’s harder to make for defensive coordinator DeMarcus Covington. But it’s not about merit this season. It’s not about what you want. It’s not about what I think. It’s about the Krafts; what they see, what they want, what they believe. Even in defeat. ____ Sent weekly directly to your inbox!

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Andrew Callahan: It’s time to forget about Jerod Mayo getting firedBRUGES, Belgium (Reuters) – Club Brugge bounced back from conceding after three minutes to beat Sporting 2-1 on Tuesday in a major boost to their hopes of advancing to the next stage of the Champions League. Geny Catamo gave the Portuguese champions the early lead with an easy tap-in from a rebound after Maximiliano Araujo’s powerful shot had struck the post but Brugge fought back to level in the 24th minute and got the winner six minutes from time with a strong close-in finish from substitute Casper Nielsen. The home side pulled level when Christos Tzolis’s strike took a wicked deflection off Eduardo Quaresma, with the goal later adjudged by UEFA to be an own goal. Sporting were awarded a penalty two minutes later, after Araujo was fouled by Andreas Skov Olsen. But after a check, the VAR officials determined the foul had occurred outside the area and English referee Anthony Taylor’s decision was changed to a free kick which Viktor Gyokeres put over the crossbar. Nielsen had barely come on when he was set up by Gustaf Nilsson’s pass and expertly hammered home the winner in the 84th minute. The result catapulted Club Brugge from 23rd to 14th place in the standings, with 10 points from six games, in a match they needed to win as their last group matches next month are at home to Juventus and then away to Manchester City. Sporting dropped to 12th spot with matches to come away to Leipzig and home against Bologna. (Writing by Mark Gleeson in Cape Town; Editing by Clare Fallon) Disclaimer: This report is auto generated from the Reuters news service. ThePrint holds no responsibility for its content. var ytflag = 0;var myListener = function() {document.removeEventListener('mousemove', myListener, false);lazyloadmyframes();};document.addEventListener('mousemove', myListener, false);window.addEventListener('scroll', function() {if (ytflag == 0) {lazyloadmyframes();ytflag = 1;}});function lazyloadmyframes() {var ytv = document.getElementsByClassName("klazyiframe");for (var i = 0; i < ytv.length; i++) {ytv[i].src = ytv[i].getAttribute('data-src');}} Save my name, email, and website in this browser for the next time I comment. Δ document.getElementById( "ak_js_1" ).setAttribute( "value", ( new Date() ).getTime() );Published 11:22 pm Sunday, December 29, 2024 By Data Skrive The NBA schedule today, including the Cleveland Cavaliers against the Golden State Warriors, should provide some fireworks. If you’re looking for live coverage of today’s NBA play, we have you covered. Take a look at the links below. Sign up for NBA League Pass to get access to games, live and on-demand, and more for the entire season and offseason. Watch ESPN originals, The Last Dance and more NBA content on ESPN+. Use our link to sign up for ESPN+ or the Disney bundle. Not all offers available in all states, please visit BetMGM for the latest promotions for your area. Must be 21+ to gamble, please wager responsibly. If you or someone you know has a gambling problem, contact 1-800-GAMBLER .

1 Brilliant Growth Stock to Buy Now and Hold for the Long TermMissouri will try to finish its nonconference home schedule unbeaten when it hosts Alabama State on Monday night in Columbia, Mo. The Tigers (10-2) have won all 10 games on their home court so far, with their only losses coming at Memphis, 83-75, in the season opener and against Illinois, 80-77, in St. Louis on Dec. 22. This is Missouri's final tune-up before starting Southeastern Conference play on Jan. 4. "The SEC has proven to be the best conference in the country so far," Tigers guard Tamar Bates said. "Being in these close games and having these lessons to look back on, we will know what we have to clean up." Missouri coach Dennis Gates saw positives in the Tigers' losses to NCAA Tournament-caliber teams. "I'm thankful for the way we respond in adversity," Gates said. "That's what ... our two losses provide. It provides Intel of how our guys have stayed connected through a little adversity ... they've stuck together and they've dug themselves out of certain situations." Guard Mark Mitchell leads Missouri with 13.8 points and 5.1 rebounds per game. Bates (12.7 ppg) and fellow guard Anthony Robinson II (10.7) have picked up the slack for the Tigers while Caleb Grill (13.6) remains sidelined with a neck injury. Tony Perkins is coming off his best game since transferring to Missouri this season from Iowa. The guard stepped up with 18 points, six rebounds, three assists and three steals against Illinois when Robinson struggled. Alabama State (4-8) will begin its Southwestern Athletic Conference slate after facing the Tigers. The Hornets, who were picked sixth in the SWAC's preseason poll, have earned victories over Omaha, Lamar, UT Martin and Division III school Virginia-Lynchburg. "When we get to January, we'll have to figure out how to make moves and get that position up where we need to be," Alabama State coach Tony Madlock said. "The most important thing, like we all know, is to get playing well going into March and then find a way to go those three games (at the SWAC tourney) and get to the NCAA Tournament." The Hornets are led by guards CJ Hines (15.8 points per game), Amarr Knox (15.6) and TJ Madlock (12.1). Hines had 25 points and six rebounds in Alabama State's 83-80 loss to Delaware State at the HBCU Classic on Dec. 20. --Field Level Media

What was the hardest game in Squid Game season 2? The cast sounds offEvaluating strategic options for iopofosine I 131 a late-stage clinical program with compelling Phase 2 data and a substantial market opportunity Focusing on advancing radiotherapeutic assets including alpha- and Auger-emitting radioconjugates into Phase 1 solid tumor studies FLORHAM PARK, N.J., Dec. 10, 2024 (GLOBE NEWSWIRE) -- Cellectar Biosciences, Inc. (NASDAQ: CLRB), a late-stage clinical biopharmaceutical company focused on the discovery, development and commercialization of drugs for the treatment of cancer, today announces a strategic update on its clinical development programs for its proprietary phospholipid ether drug conjugate platform that delivers a broad array of therapeutic modalities to target cancers. Due to recent communications with the U.S. Food and Drug Administration (FDA, or the Agency) regarding a confirmatory study to support accelerated approval and the regulatory submission for iopofosine I 131, the Company has decided to pursue strategic options for the further development and commercialization of this product candidate. The CLOVER-WaM study was conducted in accordance with earlier FDA communications from an end of Phase 2 meeting and from a meeting in early 2024, during which the Company was informed that positive results for major response rate (MRR) as the primary endpoint could be acceptable to support accelerated approval of iopofosine I 131 as a treatment for Waldenstrom’s macroglobulinemia (WM). Based upon a recent Type-C meeting with the FDA, the Company now believes that a submission seeking accelerated approval would need to be based on the MRR data from CLOVER-WaM and enrollment in a randomized, controlled confirmatory study that is designed to generate data on progression-free survival (PFS). “While iopofosine I 131’s positive WM data along with the high unmet medical need for these patients support further investment, we have determined that such a program may best be brought to market by a larger organization with greater resources. Importantly, partnering or divesting this program supports our commitment to providing this potentially life-saving drug to the patients who need it as quickly as possible,” stated James Caruso, president and CEO of Cellectar. “We believe iopofosine I 131 represents a compelling opportunity as it has shown strong efficacy and good tolerability based on our clinical studies. Moreover, the commercial work we conducted demonstrates iopofosine I 131’s substantial market opportunity based upon the product profile, which includes off-the-shelf global distribution, orphan pricing and existing unmet medical need.” Cellectar remains confident in the potential of its phospholipid ether drug conjugate platform and the targeted radiotherapies in its development pipeline. Iopofosine I 131’s clinical success validates the platform’s ability to target cancers and Cellectar will leverage its experience to focus on the development of its earlier clinical programs. Specifically, Cellectar will focus on those assets it believes have the highest therapeutic potential and opportunity for value creation. As highlighted by recent acquisitions and collaborations within the radiopharmaceutical sector, precision isotopes like alpha- and Auger-emitters have emerged as the leading therapeutics of interest. Consequently, the Company will now focus its resources on targeting solid tumors by advancing CLR 121225, its actinium-225 based program, and CLR 121125, its iodine-125 Auger-emitting program into the clinic. Cellectar expects to file Investigational New Drug applications in the first half of 2025 for both CLR-121225 and CLR-121125, which will allow the initiation of Phase 1 clinical studies in solid tumor cancers. Both programs have demonstrated robust in vivo activity, tolerability, excellent targeting and uptake in preclinical solid tumor models. The Company believes this approach will provide an expedited timeframe to achieve safety and proof-of-concept data in patients. The Company’s strategic reprioritization will impact all departments and result in an immediate reduction in headcount of approximately 60%, which should be complete by the end of the fourth quarter 2024. The Company anticipates that the implementation of the restructuring will extend its cash runway into the third quarter of 2025. “We are being methodical in our efforts to reorganize the company with the goal of conserving cash while maintaining the flexibility to execute immediate priorities and build for long-term growth and value creation. This reorganization is difficult but necessary for the future growth potential of Cellectar,” said Mr. Caruso. “I want to extend my deepest gratitude to our departing employees for their significant contributions to our work and their dedication to making a difference in the lives of patients.” About Cellectar Biosciences, Inc. Cellectar Biosciences is a late-stage clinical biopharmaceutical company focused on the discovery and development of proprietary drugs for the treatment of cancer, independently and through research and development collaborations. The company’s core objective is to leverage its proprietary Phospholipid Drug ConjugateTM (PDC) delivery platform to develop the next-generation of cancer cell-targeting treatments, delivering improved efficacy and better safety as a result of fewer off-target effects. The company’s product pipeline includes lead asset, iopofosine I 131, a small-molecule PDC designed to provide targeted delivery of iodine-131 (radioisotope), CLR 121225, an actinium-225 based program being targeted to several solid tumors with significant unmet need, such as pancreatic cancer, CLR 121125, an iodine-125 Auger-emitting program targeted in other solid tumors, such as triple negative breast, lung and colorectal, proprietary preclinical PDC chemotherapeutic programs and multiple partnered PDC assets. In addition, iopofosine I 131 is under evaluation in Phase 2b studies for relapsed or refractory multiple myeloma (MM) and central nervous system (CNS) lymphoma, alongside the CLOVER-2 Phase 1b study, targeting pediatric patients with high-grade gliomas, for which Cellectar is eligible to receive a Pediatric Review Voucher from the FDA upon approval. The FDA has also granted iopofosine I 131 Orphan Drug and Fast Track Designations for various cancer indications. New data from the CLOVER-WaM Phase 2 clinical trial were recently presented in an oral presentation at the 66th American Society of Hematology Annual Meeting and Exposition (ASH 2024). For more information, please visit www.cellectar.com or join the conversation by liking and following us on the company’s social media channels: Twitter, LinkedIn, and Facebook. Forward-Looking Statement Disclaimer This news release contains forward-looking statements. You can identify these statements by our use of words such as "may," "expect," "believe," "anticipate," "intend," "could," "estimate," "continue," "plans," or their negatives or cognates. These statements are only estimates and predictions and are subject to known and unknown risks and uncertainties that may cause actual future experience and results to differ materially from the statements made. These statements are based on our current beliefs and expectations as to such future outcomes. Drug discovery and development involve a high degree of risk. Factors that might cause such a material difference include, among others, uncertainties related to the ability to raise additional capital, uncertainties related to the disruptions at our sole source supplier of iopofosine, the ability to attract and retain partners for our technologies, the identification of lead compounds, the successful preclinical development thereof, patient enrollment and the completion of clinical studies, the FDA review process and other government regulation, our ability to obtain regulatory exclusivities, the availability of priority review vouchers, our ability to successfully develop and commercialize drug candidates, competition from other pharmaceutical companies, product pricing and third-party reimbursement. A complete description of risks and uncertainties related to our business is contained in our periodic reports filed with the Securities and Exchange Commission including our Form 10-K/A for the year ended December 31, 2023, and our Form 10-Q for the quarter ended September 30, 2024. These forward-looking statements are made only as of the date hereof, and we disclaim any obligation to update any such forward-looking statements. Contacts MEDIA: Christy Maginn Bliss Bio Health 703-297-7194 [email protected] INVESTORS: Anne Marie Fields Precision AQ 212-362-1200 [email protected] hurling legend Séamus Callanan has joined Offaly as a forwards coach. The Premier icon retired from inter-county duty last year, having won All-Ireland SHC titles in 2010, 2016 and as captain in 2019. The Drom & Inch clubman has reunited with former Tipp team-mate Brendan Maher, who is part of Offaly boss Johnny Kelly’s backroom team. The Faithful are back in the Leinster SHC next season for the first time since 2018. Offaly are All-Ireland Under-20 champions and Callanan will work with young attackers such as Kilcormac-Killoughey’s Adam Screeney, whose last-gasp goal against Castletown-Geoghegan on Sunday saw his club into the Leinster final. Saturday’s provincial showpiece at Croke Park will be their third game in as many weeks — but boss Hand would not have it any other way. He said: “In fairness to them, they came to Cusack Park and a gale-force wind blowing down the pitch. “The guys have shown that they’ve got lots of guts and they’re not afraid of mixing it. They just love hurling. “To come here and for them to win in that way against a very good, physical, very good hurling team in Castletown, I’m delighted. “The only criticism I have is we played a county final and then we waited four weeks to play the Carlow champions. “We played them last week, we played Castletown this week and we’re out again in six days, it’s not even a week. “But it’s hard to complain, this shortens the winter and keeps you busy. Otherwise I’d be up in Liffey Valley with the wife or something, so I’ll take it regardless of the quick turnaround.”ANDERSON TOWNSHIP, Ohio (AP) — Bengals quarterback Joe Burrow's home was broken into during Monday Night Football in the latest home invasion of a pro athlete in the U.S., authorities said Tuesday. No one was injured in the break-in, but the home was ransacked, according to a report provided by the Hamilton County Sheriff's Office. Deputies weren't immediately able to determine what items were stolen. A person who is employed by Burrow arrived at the Anderson Township home Monday night to find a shattered bedroom window and the home in disarray. The person called their mother, and then 911 was contacted, according to the report. Deputies reached out to neighbors in an attempt to piece together surveillance footage. “Our investigators are exploring every avenue,” public information officer Kyla Woods said. The homes of Chiefs stars Patrick Mahomes and Travis Kelce were broken into in October. In the NBA , Milwaukee Bucks forward Bobby Portis had his home broken into Nov. 2 and Minnesota Timberwolves guard Mike Conley Jr.'s home was burglarized on Sept. 15 while he was at a Minnesota Vikings game. Portis had offered a $40,000 reward for information. Both the NFL and NBA issued security alerts to players after those break-ins, urging them to take additional precautions to secure their homes. In league memos previously obtained by The Associated Press, the NFL said homes of professional athletes across multiple sports have become “increasingly targeted for burglaries by organized and skilled groups.” And the NBA revealed that the FBI has connected some burglaries to “transnational South American Theft Groups” that are “reportedly well-organized, sophisticated rings that incorporate advanced techniques and technologies, including pre-surveillance, drones, and signal jamming devices.” Some of the burglary groups have conducted extensive surveillance on targets, including attempted home deliveries and posing as grounds maintenance or joggers in the neighborhood, according to officials. AP NFL: https://apnews.com/hub/nfl

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